CTH antibody

Catalog No. ABIN7113188

The Rabbit Polyclonal anti-CTH antibody is suitable to detect CTH in samples from Human, Mouse and Rat. It has been validated for WB, IHC, ELISA, IP and FACS.

Quick Overview for CTH antibody (ABIN7113188)

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CTH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-CTH Antibody

Purpose: CTH antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: cystathionase(cystathionine gamma-lyase)

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:100-1:400, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CTH

Target: CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

Alternative Name: CTH

Background:

Synonyms: Cystathionine gamma-lyase (CGL, CSE)|Cysteine desulfhydrase|Cysteine-protein sulfhydrase|Gamma-cystathionase|Homocysteine desulfhydrase|CTH

Background: This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.This antibody is a rabbit polyclonal antibody raised against residues near the C terminus of human CTH.

Molecular Weight: 45 kDa

Gene ID: 1491

UniProt: P32929

Pathways: ER-Nucleus Signaling, Warburg Effect