DHRS9 antibody

Catalog No. ABIN7113398

The Rabbit Polyclonal anti-DHRS9 antibody has been validated for ELISA, WB, IHC and IF. It is suitable to detect DHRS9 in samples from Human, Mouse and Rat.

Quick Overview for DHRS9 antibody (ABIN7113398)

Target: DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DHRS9 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-DHRS9 Antibody

Purpose: DHRS9 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: dehydrogenase/reductase (SDR family) member 9

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DHRS9

Target: DHRS9 (Dehydrogenase/reductase (SDR Family) Member 9 (DHRS9))

Alternative Name: DHRS9

Background:

Synonyms: Dehydrogenase/reductase SDR family member 9|3-alpha hydroxysteroid dehydrogenase (3-alpha-HSD)|NADP-dependent retinol dehydrogenase/reductase|RDH-E2|RDHL|Retinol dehydrogenase 15|Short chain dehydrogenase/reductase family 9C member 4|Short-chain dehydrogenase/reductase retSDR8|Tracheobronchial epithelial cell-specific retinol dehydrogenase (RDH-TBE)|DHRS9|RDH15|SDR9C4

Background: This gene encodes a member of the short-chain dehydrogenases/reductases (SDR) family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. This protein demonstrates oxidoreductase activity toward hydroxysteroids and is able to convert 3-alpha-tetrahydroprogesterone to dihydroxyprogesterone and 3-alpha-androstanediol to dihydroxyprogesterone in the cytoplasm, and may additionally function as a transcriptional repressor in the nucleus. Alternative splicing results in multiple transcript variants.

Molecular Weight: 33 kDa

Gene ID: 10170

UniProt: Q9BPW9

Pathways: C21-Steroid Hormone Metabolic Process