DLL4 antibody

Catalog No. ABIN7113410

The Rabbit Polyclonal anti-DLL4 antibody has been validated for WB, ELISA and IP. It is suitable to detect DLL4 in samples from Human and Mouse.

Quick Overview for DLL4 antibody (ABIN7113410)

Target: DLL4 (delta-Like 4 (DLL4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DLL4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-DLL4 Antibody

Purpose: DLL4 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: delta-like 4(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DLL4

Target: DLL4 (delta-Like 4 (DLL4))

Alternative Name: DLL4

Background:

Synonyms: Delta-like protein 4|Drosophila Delta homolog 4 (Delta4)|DLL4

Background: Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis, negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).

Molecular Weight: 75-80 kDa

Gene ID: 54567

UniProt: Q9NR61

Pathways: Notch Signaling