Deltex Homolog 3 antibody

Catalog No. ABIN7113413

The Rabbit Polyclonal anti-Deltex Homolog 3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect Deltex Homolog 3 in samples from Human and Mouse.

Quick Overview for Deltex Homolog 3 antibody (ABIN7113413)

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Deltex Homolog 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Deltex Homolog 3 Antibody

Purpose: DTX3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: deltex homolog 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Deltex Homolog 3

Target: Deltex Homolog 3 (DTX3) (Deltex Homolog 3 (Drosophila) (DTX3))

Alternative Name: DTX3

Background:

Synonyms: Probable E3 ubiquitin-protein ligase DTX3|Protein deltex-3 (Deltex3)|RING finger protein 154|RING-type E3 ubiquitin transferase DTX3|DTX3|RNF154

Background: Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context(By similarity). Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.

Molecular Weight: 38 kDa

Gene ID: 196403

UniProt: Q8N9I9

Pathways: Notch Signaling