DCXR antibody

Catalog No. ABIN7113470

The Rabbit Polyclonal anti-DCXR antibody is suitable to detect DCXR in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for DCXR antibody (ABIN7113470)

Target: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DCXR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-DCXR Antibody

Purpose: DCXR antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: dicarbonyl/L-xylulose reductase

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for DCXR

Target: DCXR (Dicarbonyl/L-Xylulose Reductase (DCXR))

Alternative Name: DCXR

Background:

Synonyms: L-xylulose reductase (XR)|Carbonyl reductase II|Dicarbonyl/L-xylulose reductase|Kidney dicarbonyl reductase (kiDCR)|Short chain dehydrogenase/reductase family 20C member 1|Sperm surface protein P34H|DCXR|SDR20C1

Background: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules.

Molecular Weight: 26 kDa

Gene ID: 51181

UniProt: Q7Z4W1

Pathways: Glycosaminoglycan Metabolic Process, Monocarboxylic Acid Catabolic Process