ERLIN1 antibody

Catalog No. ABIN7113870

The Rabbit Polyclonal anti-ERLIN1 antibody (ABIN7113870) specifically detects ERLIN1 in WB, ELISA, IHC, IP and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ERLIN1 antibody (ABIN7113870)

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-ERLIN1 Antibody

Purpose: ERLIN1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ER lipid raft associated 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ERLIN1

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Alternative Name: ERLIN1

Background:

Synonyms: Erlin-1|Endoplasmic reticulum lipid raft-associated protein 1|Protein KE04|Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 1 (SPFH domain-containing protein 1)|ERLIN1|C10orf69|KE04|KEO4|SPFH1

Background: Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

Molecular Weight: 39 kDa

Gene ID: 10613

UniProt: O75477