ERLIN1 antibody

Catalog No. ABIN7113870

Product Details anti-ERLIN1 Antibody

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERLIN1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ER lipid raft associated 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ERLIN1

Target: ERLIN1 (ER Lipid Raft Associated 1 (ERLIN1))

Alternative Name: ERLIN1 (ERLIN1 Products)

Synonyms: C10orf69 antibody, Erlin-1 antibody, KE04 antibody, KEO4 antibody, SPFH1 antibody, wu:fa10h05 antibody, wu:fb19h05 antibody, zgc:110547 antibody, 2810439N09Rik antibody, C80197 antibody, Keo4 antibody, Spfh1 antibody, RGD1307058 antibody, erlin-1 antibody, ER lipid raft associated 1 antibody, ERLIN1 antibody, erlin1 antibody, Erlin1 antibody

Background: Synonyms:C10orf69, KE04, KEO4, SPFH1 Background:Component of the ERLIN1/ERLIN2 complex which mediates the endoplasmic reticulum-associated degradation(ERAD) of inositol 1,4,5-trisphosphate receptors(IP3Rs). Involved in regulation of cellular cholesterol homeostasis by regulation the SREBP signaling pathway. Binds cholesterol and may promote ER retention of the SCAP-SREBF complex(PubMed:24217618).

Molecular Weight: 39 kDa

Gene ID: 10613

UniProt: O75477