ESCO2 antibody

Catalog No. ABIN7113894

The Rabbit Polyclonal anti-ESCO2 antibody (ABIN7113894) specifically detects ESCO2 in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for ESCO2 antibody (ABIN7113894)

Target: ESCO2 (Establishment of Cohesion 1 Homolog 2 (ESCO2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESCO2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ESCO2 Antibody

Purpose: ESCO2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: establishment of cohesion 1 homolog 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ESCO2

Target: ESCO2 (Establishment of Cohesion 1 Homolog 2 (ESCO2))

Alternative Name: ESCO2

Background:

Synonyms: N-acetyltransferase ESCO2|Establishment factor-like protein 2 (EFO2, EFO2p, hEFO2)|Establishment of cohesion 1 homolog 2 (ECO1 homolog 2)|ESCO2

Background: Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.

Molecular Weight: 65-70 kDa

Gene ID: 157570

UniProt: Q56NI9

Pathways: Positive Regulation of Endopeptidase Activity