ESX Homeobox 1 antibody

Catalog No. ABIN7113905

The Rabbit Polyclonal anti-ESX Homeobox 1 antibody has been validated for WB, ELISA and IP. It is suitable to detect ESX Homeobox 1 in samples from Human and Mouse.

Quick Overview for ESX Homeobox 1 antibody (ABIN7113905)

Target: ESX Homeobox 1 (ESX1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ESX Homeobox 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-ESX Homeobox 1 Antibody

Purpose: ESX1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ESX homeobox 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ESX Homeobox 1

Target: ESX Homeobox 1 (ESX1)

Alternative Name: ESX1

Background:

Synonyms: Homeobox protein ESX1|Extraembryonic, spermatogenesis, homeobox 1|Homeobox protein ESX1-N|Homeobox protein ESX1-C|ESX1|ESX1L|ESX1R

Background: May coordinately regulate cell cycle progression and transcription during spermatogenesis. Inhibits degradation of polyubiquitinated cyclin A and cyclin B1 and thereby arrests the cell cycle at early M phase. ESXR1-N acts as a transcriptional repressor. Binds to the sequence 5'-TAATGTTATTA-3' which is present within the first intron of the KRAS gene and inhibits its expression. ESXR1-C has the ability to inhibit cyclin turnover.

Molecular Weight: 65 kDa

Gene ID: 80712

UniProt: Q8N693