EXD2 antibody (AA 400-621)

Catalog No. ABIN7114003

This Rabbit Polyclonal antibody specifically detects EXD2 in WB, ELISA, IHC, IF and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for EXD2 antibody (AA 400-621) (ABIN7114003)

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EXD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Product Details anti-EXD2 Antibody

Binding Specificity: AA 400-621

Purpose: EXD2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 400-621aa

Immunogen: exonuclease 3'-5' domain containing 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for EXD2

Target: EXD2 (Exonuclease 3'-5' Domain Containing 2 (EXD2))

Alternative Name: EXD2

Background:

Synonyms: Exonuclease 3'-5' domain-containing protein 2|3'-5' exoribonuclease EXD2|Exonuclease 3'-5' domain-like-containing protein 2|EXD2|C14orf114|EXDL2

Background: Exonuclease required for double-strand breaks resection and efficient homologous recombination. Plays a key role in controlling the initial steps of chromosomal break repair, it is recruited to chromatin in a damage-dependent manner and functionally interacts with the MRN complex to accelerate resection through its 3'-5' exonuclease activity, which efficiently processes double-stranded DNA substrates containing nicks.

Molecular Weight: 56 kDa

Gene ID: 55218

UniProt: Q9NVH0