FANCL antibody

Catalog No. ABIN7114122

The Rabbit Polyclonal anti-FANCL antibody (ABIN7114122) specifically detects FANCL in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FANCL antibody (ABIN7114122)

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-FANCL Antibody

Purpose: FANCL antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Fanconi anemia, complementation group L

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FANCL

Target: FANCL (Fanconi Anemia, Complementation Group L (FANCL))

Alternative Name: FANCL

Background:

Synonyms: E3 ubiquitin-protein ligase FANCL|Fanconi anemia group L protein|Fanconi anemia-associated polypeptide of 43 kDa (FAAP43)|RING-type E3 ubiquitin transferase FANCL|FANCL|PHF9

Background: Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.

Molecular Weight: 41-43 kDa

Gene ID: 55120

UniProt: Q9NW38

Pathways: DNA Damage Repair