FECH antibody

Catalog No. ABIN7114185

The Rabbit Polyclonal anti-FECH antibody (ABIN7114185) specifically detects FECH in WB, IHC and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FECH antibody (ABIN7114185)

Target: FECH (Ferrochelatase (FECH))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FECH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-FECH Antibody

Purpose: FECH antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ferrochelatase (protoporphyria)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FECH

Target: FECH (Ferrochelatase (FECH))

Alternative Name: FECH

Background:

Synonyms: Ferrochelatase, mitochondrial|Heme synthase|Protoheme ferro-lyase|FECH

Background: The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Molecular Weight: 50 kDa

Gene ID: 2235

UniProt: P22830

Pathways: Transition Metal Ion Homeostasis