FBLIM1 antibody

Catalog No. ABIN7114242

The Rabbit Polyclonal anti-FBLIM1 antibody (ABIN7114242) specifically detects FBLIM1 in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FBLIM1 antibody (ABIN7114242)

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FBLIM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-FBLIM1 Antibody

Purpose: FBLIM1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: filamin binding LIM protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FBLIM1

Target: FBLIM1 (Filamin Binding LIM Protein 1 (FBLIM1))

Alternative Name: FBLIM1

Background:

Synonyms: Filamin-binding LIM protein 1 (FBLP-1)|Migfilin|Mitogen-inducible 2-interacting protein (MIG2-interacting protein)|FBLIM1|FBLP1

Background: Serves as an anchoring site for cell-ECM adhesion proteins and filamin-containing actin filaments. Is implicated in cell shape modulation(spreading) and motility. May participate in the regulation of filamin-mediated cross-linking and stabilization of actin filaments. May also regulate the assembly of filamin-containing signaling complexes that control actin assembly. Promotes dissociation of FLNA from ITGB3 and ITGB7. Promotes activation of integrins and regulates integrin-mediated cell-cell adhesion.

Molecular Weight: 45-48 kDa

Gene ID: 54751

UniProt: Q8WUP2