FOLR1 antibody (AA 60-100)

Catalog No. ABIN7114277

The Mouse Monoclonal anti-FOLR1 antibody has been validated for WB, ELISA and IHC. It is suitable to detect FOLR1 in samples from Human.

Quick Overview for FOLR1 antibody (AA 60-100) (ABIN7114277)

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FOLR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 6A8

Product Details anti-FOLR1 Antibody

Binding Specificity: AA 60-100

Purpose: FOLR1 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 60-100aa

Immunogen: folate receptor 1

Isotype: IgG1

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for FOLR1

Target: FOLR1 (Folate Receptor 1 (Adult) (FOLR1))

Alternative Name: FOLR1

Background:

Synonyms: Folate receptor alpha (FR-alpha)|Adult folate-binding protein (FBP)|Folate receptor 1|Folate receptor, adult|KB cells FBP|Ovarian tumor-associated antigen MOv18|FOLR1|FOLR

Background: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.

Molecular Weight: 38 kDa

Gene ID: 2348

UniProt: P15328

Pathways: Dicarboxylic Acid Transport