GALC antibody (AA 40-300)

Catalog No. ABIN7114452

The Rabbit Polyclonal anti-GALC antibody (ABIN7114452) specifically detects GALC in WB, IHC and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GALC antibody (AA 40-300) (ABIN7114452)

Target: GALC (Galactosylceramidase (GALC))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-GALC Antibody

Binding Specificity: AA 40-300

Purpose: GALC antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 40-300aa

Immunogen: galactosylceramidase

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GALC

Target: GALC (Galactosylceramidase (GALC))

Alternative Name: GALC

Background:

Synonyms: Galactocerebrosidase (GALCERase)|Galactocerebroside beta-galactosidase|Galactosylceramidase|Galactosylceramide beta-galactosidase|GALC

Background: This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Molecular Weight: 77 kDa

Gene ID: 2581

UniProt: P54803