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Glutaredoxin 2 antibody

GRX2 Reactivity: Human, Rat, Mouse WB, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7114635
  • Target See all Glutaredoxin 2 (GRX2) Antibodies
    Glutaredoxin 2 (GRX2)
    Reactivity
    • 40
    • 22
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human, Rat, Mouse
    Host
    • 34
    • 6
    Rabbit
    Clonality
    • 38
    • 2
    Polyclonal
    Conjugate
    • 20
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Glutaredoxin 2 antibody is un-conjugated
    Application
    • 33
    • 21
    • 13
    • 13
    • 9
    • 9
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    Western Blotting (WB), ELISA
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    glutaredoxin 2
    Isotype
    IgG
    Top Product
    Discover our top product GRX2 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    Glutaredoxin 2 (GRX2)
    Alternative Name
    GLRX2 (GRX2 Products)
    Synonyms
    ECK1049 antibody, JW1051 antibody, CGI-133 antibody, GRX2 antibody, 1700010P22Rik antibody, AI645710 antibody, Grx2 antibody, glutaredoxin 2 (Grx2) antibody, glutaredoxin Grx2 antibody, thioredoxin antibody, glutaredoxin 2 antibody, glutaredoxin 2 (thioltransferase) antibody, grxB antibody, grx2 antibody, AF_RS10790 antibody, GLRX2 antibody, Glrx2 antibody
    Background
    Synonyms:GRX2 Background:Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione(GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.
    Molecular Weight
    16 kDa
    Gene ID
    51022
    UniProt
    Q9NS18
    Pathways
    Cell RedoxHomeostasis
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