GLRA3 antibody

Catalog No. ABIN7114692

The Rabbit Polyclonal anti-GLRA3 antibody (ABIN7114692) specifically detects GLRA3 in WB and ELISA. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for GLRA3 antibody (ABIN7114692)

Target: GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLRA3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GLRA3 Antibody

Purpose: GLRA3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: glycine receptor, alpha 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GLRA3

Target: GLRA3 (GLRa3) (Glycine Receptor, alpha 3 (GLRa3))

Alternative Name: GLRA3

Background:

Synonyms: Glycine receptor subunit alpha-3|GLRA3

Background: Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine(PubMed:9677400, PubMed:26416729). Channel characteristics depend on the subunit composition, heteropentameric channels display faster channel closure(By similarity). Plays an important role in the down-regulation of neuronal excitability(By similarity). Contributes to the generation of inhibitory postsynaptic currents(By similarity). Contributes to increased pain perception in response to increased prostaglandin E2 levels(By similarity). Plays a role in cellular responses to ethanol(By similarity).

Molecular Weight: 54 kDa

Gene ID: 8001

UniProt: O75311