K-RAS antibody

Catalog No. ABIN7114805

The Rabbit Polyclonal anti-K-RAS antibody has been validated for WB, ELISA, IHC and IP. It is suitable to detect K-RAS in samples from Human, Rat and Mouse.

Quick Overview for K-RAS antibody (ABIN7114805)

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This K-RAS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-K-RAS Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:1000, IHC: 1:50 - 1:200, IP: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for K-RAS

Target: K-RAS (KRAS) (GTPase Kras (KRAS))

Alternative Name: KRAS

Target Type: Viral Protein

Background: Synonyms:C K RAS, c Ki ras, GTPase KRas, K Ras 2, K RAS2A, K RAS2B, K RAS4A, K RAS4B, KI RAS, KRAS, KRAS1, KRAS2, KRAS2B speicifc, Krasa, Krasb, NS3, RASK2 Background:Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the regulation of cell proliferation(PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes(TSGs) in colorectal cancer(CRC) cells in a ZNF304-dependent manner(PubMed:24623306).

Molecular Weight: 21 kDa

Gene ID: 3845

UniProt: P01116