GBP2 antibody

Catalog No. ABIN7114834

This Rabbit Polyclonal antibody specifically detects GBP2 in WB, ELISA and IHC. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for GBP2 antibody (ABIN7114834)

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-GBP2 Antibody

Purpose: GBP2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: guanylate binding protein 2, interferon-inducible

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:3000, IHC: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for GBP2

Target: GBP2 (Guanylate Binding Protein 2, Interferon-Inducible (GBP2))

Alternative Name: GBP2

Background:

Synonyms: Guanylate-binding protein 2|GTP-binding protein 2 (GBP-2, HuGBP-2)|Guanine nucleotide-binding protein 2|Interferon-induced guanylate-binding protein 2|GBP2

Background: Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP(PubMed:8706832). Exhibits antiviral activity against influenza virus. Promote oxidative killing and deliver antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes(By similarity).

Molecular Weight: 67 kDa

Gene ID: 2634

UniProt: P32456

Pathways: Cellular Response to Molecule of Bacterial Origin