HSPA9 antibody

Catalog No. ABIN7114892

The Rabbit Polyclonal anti-HSPA9 antibody has been validated for WB, IHC, ELISA, IF, IP and FACS. It is suitable to detect HSPA9 in samples from Human, Rat and Mouse.

Quick Overview for HSPA9 antibody (ABIN7114892)

Target: HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPA9 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Product Details anti-HSPA9 Antibody

Purpose: HSPA9 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: heat shock 70kDa protein 9(mortalin)

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:4000, IP: 1:1000-1:4000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HSPA9

Target: HSPA9 (Heat Shock 70kDa Protein 9 (Mortalin) (HSPA9))

Alternative Name: HSPA9

Background:

Synonyms: Stress-70 protein, mitochondrial|75 kDa glucose-regulated protein (GRP-75)|Heat shock 70 kDa protein 9|Mortalin (MOT)|Peptide-binding protein 74 (PBP74)|HSPA9|GRP75|HSPA9B|mt-HSP70

Background: GRP75(also known as mortalin, HSPA9 or mt-Hsp70) is a constitutively expressed member of the HSPA(HSP70) family of heat-shock proteins. It is located in the mitochondrial matrix and anti-GRP75 is commonly used as the marker for mitochondria. It has been reported that GRP75 is enriched in cancer cells and contributes to carcinogenesis. In addition, decreased expression level of GRP75 has been found in neurodegenerative disorders like Parkinson's disease.

Molecular Weight: 74 kDa

UniProt: P38646