HPGDS antibody

Catalog No. ABIN7114929

The Rabbit Polyclonal anti-HPGDS antibody (ABIN7114929) specifically detects HPGDS in WB, ELISA and IHC. The antibody is reactive with Human and Mouse samples.

Quick Overview for HPGDS antibody (ABIN7114929)

Target: HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-HPGDS Antibody

Purpose: HPGDS antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: prostaglandin D2 synthase, hematopoietic

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HPGDS

Target: HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))

Alternative Name: HPGDS

Background:

Synonyms: Hematopoietic prostaglandin D synthase (H-PGDS)|GST class-sigma|Glutathione S-transferase|Glutathione-dependent PGD synthase|Glutathione-requiring prostaglandin D synthase|Prostaglandin-H2 D-isomerase|HPGDS|GSTS|PGDS|PTGDS2

Background: Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.

Molecular Weight: 26-30 kDa

Gene ID: 27306

UniProt: O60760