HPGDS antibody

Catalog No. ABIN7228960

The Rabbit Polyclonal anti-HPGDS antibody is suitable to detect HPGDS in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for HPGDS antibody (ABIN7228960)

Target: HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGDS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-HPGDS Antibody

Purpose: Rabbit Anti-HPGDS Polyclonal Antibody

Specificity: The antibody detects endogenous levels of HPGDS protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HPGDS protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for HPGDS

Target: HPGDS (Hematopoietic Prostaglandin D Synthase (HPGDS))

Alternative Name: HPGDS

Background: Hematopoietic prostaglandin D synthase, H-PGDS, GST class-sigma, Glutathione S-transferase, Glutathione-dependent PGD synthase, Glutathione-requiring prostaglandin D synthase, Prostaglandin-H2 D-isomeraseProstaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes. HPGDS (Hematopoietic Prostaglandin D Synthase) is a Protein Coding gene. Diseases associated with HPGDS include Holoprosencephaly 2 and Prostate Leiomyosarcoma. Among its related pathways are Glutathione metabolism and Metabolism.

Molecular Weight: 21kD

Gene ID: 27306

UniProt: O60760