HMOX1 antibody (AA 1-267)

Catalog No. ABIN7114932

The Rabbit Polyclonal anti-HMOX1 antibody (ABIN7114932) specifically detects HMOX1 in WB, IHC, IP, ELISA and IF. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for HMOX1 antibody (AA 1-267) (ABIN7114932)

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMOX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Product Details anti-HMOX1 Antibody

Binding Specificity: AA 1-267

Purpose: HMOX1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-267aa

Immunogen: heme oxygenase(decycling) 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:2000, IHC: 1:100-1:400, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HMOX1

Target: HMOX1 (Heme Oxygenase (Decycling) 1 (HMOX1))

Alternative Name: HMOX1

Background:

Synonyms: Heme oxygenase 1 (HO-1)|Heme oxygenase 1 soluble form|HMOX1|HO|HO1

Background: Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.

Molecular Weight: 33 kDa

Gene ID: 3162

UniProt: P09601

Pathways: Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome