HOMER2 antibody

Catalog No. ABIN7115101

This Rabbit Polyclonal antibody specifically detects HOMER2 in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for HOMER2 antibody (ABIN7115101)

Target: HOMER2 (Homer Homolog 2 (HOMER2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOMER2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-HOMER2 Antibody

Purpose: HOMER2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: homer homolog 2(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HOMER2

Target: HOMER2 (Homer Homolog 2 (HOMER2))

Alternative Name: HOMER2

Background:

Synonyms: Homer protein homolog 2 (Homer-2)|Cupidin|HOMER2

Background: Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses(PubMed:9808459). Required for normal hearing(PubMed:25816005).

Molecular Weight: 39 kDa

Gene ID: 9455

UniProt: Q9NSB8

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling