HOPX antibody

Catalog No. ABIN7115108

The Rabbit Polyclonal anti-HOPX antibody is suitable to detect HOPX in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IF.

Quick Overview for HOPX antibody (ABIN7115108)

Target: HOPX (HOP Homeobox (HOPX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOPX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-HOPX Antibody

Purpose: HOPX antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: HOP homeobox

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HOPX

Target: HOPX (HOP Homeobox (HOPX))

Alternative Name: HOPX

Background:

Synonyms: Homeodomain-only protein|Lung cancer-associated Y protein|Not expressed in choriocarcinoma protein 1|Odd homeobox protein 1|HOPX|HOD|HOP|LAGY|NECC1|OB1

Background: Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase(HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy(By similarity). May act as a tumor suppressor.

Molecular Weight: 8-12 kDa

Gene ID: 84525

UniProt: Q9BPY8

Pathways: Regulation of Muscle Cell Differentiation