HPGD antibody

Catalog No. ABIN7115144

The Rabbit Polyclonal anti-HPGD antibody has been validated for ELISA, WB and IHC. It is suitable to detect HPGD in samples from Human, Mouse and Rat.

Quick Overview for HPGD antibody (ABIN7115144)

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HPGD antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-HPGD Antibody

Purpose: HPGD antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: hydroxyprostaglandin dehydrogenase 15-(NAD)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for HPGD

Target: HPGD (Hydroxyprostaglandin Dehydrogenase 15-(NAD) (HPGD))

Alternative Name: HPGD

Background:

Synonyms: 15-hydroxyprostaglandin dehydrogenase [NAD(+)] (15-PGDH)|Eicosanoid/docosanoid dehydrogenase [NAD(+)]|Prostaglandin dehydrogenase 1|Short chain dehydrogenase/reductase family 36C member 1|HPGD|PGDH1|SDR36C1

Background: This gene encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 29 kDa

Gene ID: 3248

UniProt: P15428