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IKZF1 antibody

This anti-IKZF1 antibody is a Rabbit Polyclonal antibody detecting IKZF1 in WB, ELISA, IHC and IP. Suitable for Human, Mouse and Rat.
Catalog No. ABIN7115178

Quick Overview for IKZF1 antibody (ABIN7115178)

Target

See all IKZF1 Antibodies
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

Reactivity

  • 57
  • 38
  • 16
  • 5
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  • 4
  • 4
  • 4
  • 1
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Human, Mouse, Rat

Host

  • 59
  • 12
  • 2
Rabbit

Clonality

  • 57
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Polyclonal

Conjugate

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  • 4
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IKZF1 antibody is un-conjugated

Application

  • 57
  • 23
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  • 13
  • 13
  • 9
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  • 4
  • 4
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  • 1
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  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
  • Purification

    Immunogen affinity purified

    Purity

    ≥95 % as determined by SDS-PAGE

    Immunogen

    IKAROS family zinc finger 1(Ikaros)

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Expiry Date

    12 months
  • Target

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    Alternative Name

    IKZF1

    Background

    Synonyms:IK1, IKAROS, LYF1, ZNFN1A1 Background:Transcription regulator of hematopoietic cell differentiation(PubMed:17934067). Binds gamma-satellite DNA(PubMed:17135265, PubMed:19141594). Plays a role in the development of lymphocytes, B-and T-cells. Binds and activates the enhancer(delta-A element) of the CD3-delta gene. Repressor of the TDT(fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF(SWI/SNF), in a single complex(PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells(RPCs)(By similarity). Function is isoform-specific and is modulated by dominant-negative inactive isoforms(PubMed:17135265, PubMed:17934067).

    Molecular Weight

    53 kDa

    Gene ID

    10320

    UniProt

    Q13422

    Pathways

    Production of Molecular Mediator of Immune Response
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