IL11RA antibody

Catalog No. ABIN7115415

The Rabbit Polyclonal anti-IL11RA antibody (ABIN7115415) specifically detects IL11RA in WB, ELISA, IF and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IL11RA antibody (ABIN7115415)

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL11RA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Product Details anti-IL11RA Antibody

Purpose: IL11RA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: interleukin 11 receptor, alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL11RA

Target: IL11RA (Interleukin 11 Receptor, alpha (IL11RA))

Alternative Name: IL11RA

Background:

Synonyms: Interleukin-11 receptor subunit alpha (IL-11 receptor subunit alpha, IL-11R subunit alpha, IL-11R-alpha, IL-11RA)|Soluble interleukin-11 receptor subunit alpha (sIL-11R, sIL-11RA, sIL11RA)|IL11RA

Background: Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Molecular Weight: 45 kDa

Gene ID: 3590

UniProt: Q14626

Pathways: JAK-STAT Signaling, Growth Factor Binding