IL17RC antibody

Catalog No. ABIN7115427

The Rabbit Polyclonal anti-IL17RC antibody (ABIN7115427) specifically detects IL17RC in WB and ELISA. The antibody is reactive with Human and Mouse samples.

Quick Overview for IL17RC antibody (ABIN7115427)

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RC antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-IL17RC Antibody

Purpose: IL17RC antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: interleukin 17 receptor C

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL17RC

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Alternative Name: IL17RC

Background:

Synonyms: Interleukin-17 receptor C (IL-17 receptor C, IL-17RC)|Interleukin-17 receptor homolog (IL17Rhom)|Interleukin-17 receptor-like protein (IL-17RL)|ZcytoR14|IL17RC

Background: Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA(PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA(PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA(PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1(PubMed:16785495). Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F.

Molecular Weight: 45-50 kDa

Gene ID: 84818

UniProt: Q8NAC3