IL17RC antibody (C-Term)

Catalog No. ABIN6257289

Product Details anti-IL17RC Antibody

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL17RC antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Specificity: IL17RC Antibody detects endogenous levels of total IL17RC.

Purification: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IL17RC, corresponding to a region within C-terminal amino acids.

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20 °C. Stable for 12 months from date of receipt.

Expiry Date: 12 months

Target Details for IL17RC

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Alternative Name: IL17RC (IL17RC Products)

Synonyms: IL17-RL antibody, IL17RL antibody, 1110025H02Rik antibody, Gm19850 antibody, IL-17RC antibody, IL17-RC antibody, Il17rl antibody, interleukin 17 receptor C antibody, Il17rc antibody, IL17RC antibody

Background:

Description: Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495). Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971). Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633). Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495).

Gene: IL17RC

Molecular Weight: 70 kDa

Gene ID: 84818

UniProt: Q8NAC3