IL-4 antibody (AA 25-153)

Catalog No. ABIN7115466

This anti-IL-4 antibody is a Mouse Monoclonal antibody detecting IL-4 in WB, ELISA and IHC. Suitable for Human and Rat.

Quick Overview for IL-4 antibody (AA 25-153) (ABIN7115466)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL-4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 5A0

Product Details anti-IL-4 Antibody

Binding Specificity: AA 25-153

Purpose: IL4 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 25-153aa

Immunogen: interleukin 4

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL4

Background:

Synonyms: Interleukin-4 (IL-4)|B-cell stimulatory factor 1 (BSF-1)|Binetrakin|Lymphocyte stimulatory factor 1|Pitrakinra|IL4

Background: Participates in at least several B-cell activation processes as well as of other cell types(PubMed:3016727). It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE(CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages(By similarity).

Molecular Weight: 18 kDa

Gene ID: 3565

UniProt: P05112

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation