KLF15 antibody (AA 1-416)

Catalog No. ABIN7115731

This Mouse Monoclonal antibody specifically detects KLF15 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for KLF15 antibody (AA 1-416) (ABIN7115731)

Target: KLF15 (Kruppel-Like Factor 15 (KLF15))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLF15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1C10

Product Details anti-KLF15 Antibody

Binding Specificity: AA 1-416

Purpose: KLF15 antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1-416aa

Immunogen: Kruppel-like factor 15

Isotype: IgG2a

Application Details

Application Notes: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for KLF15

Target: KLF15 (Kruppel-Like Factor 15 (KLF15))

Alternative Name: KLF15

Background:

Synonyms: Krueppel-like factor 15|Kidney-enriched krueppel-like factor|KLF15|KKLF

Background: Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart(By similarity). Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4(By similarity). Involved in podocyte differentiation(By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.

Molecular Weight: 45 kDa

Gene ID: 28999

UniProt: Q9UIH9