Leupaxin antibody

Catalog No. ABIN7115856

The Rabbit Polyclonal anti-Leupaxin antibody (ABIN7115856) specifically detects Leupaxin in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for Leupaxin antibody (ABIN7115856)

Target: Leupaxin (LPXN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Leupaxin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Leupaxin Antibody

Purpose: LPXN antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: leupaxin

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Leupaxin

Target: Leupaxin (LPXN)

Alternative Name: LPXN

Background:

Synonyms: Leupaxin|LPXN|LDLP

Background: Transcriptional coactivator for androgen receptor(AR) and serum response factor(SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin-induced tyrosine phosphorylation of paxillin(PXN). May play a critical role as an adapter protein in the formation of the adhesion zone in osteoclasts. Negatively regulates B-cell antigen receptor(BCR) signaling.

Molecular Weight: 50-60 kDa

Gene ID: 9404

UniProt: O60711