MAP1LC3A antibody (cleaved)

Catalog No. ABIN7116292

This Rabbit Polyclonal antibody specifically detects MAP1LC3A in WB, IHC and ELISA. It exhibits reactivity toward Mouse and Rat.

Quick Overview for MAP1LC3A antibody (cleaved) (ABIN7116292)

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAP1LC3A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-MAP1LC3A Antibody

Binding Specificity: cleaved

Purpose: Cleaved LC3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: microtubule-associated protein 1 light chain 3 alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MAP1LC3A

Target: MAP1LC3A (Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A))

Alternative Name: LC3

Background:

Synonyms: Microtubule-associated proteins 1A/1B light chain 3A|Autophagy-related protein LC3 A|Autophagy-related ubiquitin-like modifier LC3 A|MAP1 light chain 3-like protein 1|MAP1A/MAP1B light chain 3 A (MAP1A/MAP1B LC3 A)|Microtubule-associated protein 1 light chain 3 alpha|MAP1LC3A

Background: MAP1A and MAP1B are microtubule-associated proteins which mediate the physical interactions between microtubules and components of the cytoskeleton. MAP1A and MAP1B each consist of a heavy chain subunit and multiple light chain subunits. The protein encoded by this gene is one of the light chain subunits and can associate with either MAP1A or MAP1B. Two transcript variants encoding different isoforms have been found for this gene. The expression of variant 1 is suppressed in many tumor cell lines, suggesting that may be involved in carcinogenesis.

Molecular Weight: Refer to figures

Gene ID: 84557

UniProt: Q9H492

Pathways: Autophagy