MX1 antibody

Catalog No. ABIN7116666

The Rabbit Polyclonal anti-MX1 antibody (ABIN7116666) specifically detects MX1 in WB, IHC, ELISA, IP and IF. The antibody is reactive with Human and Mouse samples.

Quick Overview for MX1 antibody (ABIN7116666)

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-MX1 Antibody

Purpose: MX1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Myxovirus resistance protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for MX1

Target: MX1 (Myxovirus Resistance Protein 1 (MX1))

Alternative Name: MX1

Background:

Synonyms: Interferon-induced GTP-binding protein Mx1|Interferon-induced protein p78 (IFI-78K)|Interferon-regulated resistance GTP-binding protein MxA|Myxoma resistance protein 1|Myxovirus resistance protein 1|Interferon-induced GTP-binding protein Mx1, N-terminally processed|MX1

Background: Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.

Molecular Weight: 76 kDa

Gene ID: 4599

UniProt: P20591