NCKIPSD antibody

Catalog No. ABIN7116757

This Rabbit Polyclonal antibody specifically detects NCKIPSD in WB, ELISA, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NCKIPSD antibody (ABIN7116757)

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NCKIPSD antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-NCKIPSD Antibody

Purpose: NCKIPSD antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NCK interacting protein with SH3 domain

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NCKIPSD

Target: NCKIPSD (NCK Interacting Protein with SH3 Domain (NCKIPSD))

Alternative Name: NCKIPSD

Background:

Synonyms: NCK-interacting protein with SH3 domain|54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein (VIP54)|90 kDa SH3 protein interacting with Nck|AF3p21|Dia-interacting protein 1 (DIP-1)|Diaphanous protein-interacting protein|SH3 adapter protein SPIN90|WASP-interacting SH3-domain protein (WISH)|Wiskott-Aldrich syndrome protein-interacting protein|NCKIPSD|AF3P21|SPIN90

Background: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1(DRF1). Induces microspike formation, in vivo(By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42(By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.

Molecular Weight: 80 kDa

Gene ID: 51517

UniProt: Q9NZQ3

Pathways: Protein targeting to Nucleus