NPHP3 antibody

Catalog No. ABIN7116776

The Rabbit Polyclonal anti-NPHP3 antibody is suitable to detect NPHP3 in samples from Human and Mouse. It has been validated for WB, ELISA, IHC, IP and IF.

Quick Overview for NPHP3 antibody (ABIN7116776)

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPHP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-NPHP3 Antibody

Purpose: NPHP3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nephronophthisis 3(adolescent)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NPHP3

Target: NPHP3 (Nephronophthisis 3 (Adolescent) (NPHP3))

Alternative Name: NPHP3

Background:

Synonyms: Nephrocystin-3|NPHP3|KIAA2000

Background: Required for normal ciliary development and function. Inhibits disheveled-1-induced canonical Wnt-signaling activity and may also play a role in the control of non-canonical Wnt signaling which regulates planar cell polarity. Probably acts as a molecular switch between different Wnt signaling pathways. Required for proper convergent extension cell movements.

Molecular Weight: 145-151 kDa

Gene ID: 27031

UniProt: Q7Z494

Pathways: cAMP Metabolic Process