NKIRAS2 antibody

Catalog No. ABIN7116853

This Rabbit Polyclonal antibody specifically detects NKIRAS2 in ELISA, WB and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NKIRAS2 antibody (ABIN7116853)

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NKIRAS2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-NKIRAS2 Antibody

Purpose: NKIRAS2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NFKB inhibitor interacting Ras-like 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NKIRAS2

Target: NKIRAS2 (NFKB Inhibitor Interacting Ras-Like 2 (NKIRAS2))

Alternative Name: NKIRAS2

Background:

Synonyms: NF-kappa-B inhibitor-interacting Ras-like protein 2|I-kappa-B-interacting Ras-like protein 2 (Kappa B-Ras protein 2, KappaB-Ras2)|NKIRAS2|KBRAS2

Background: Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta(NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB(By similarity).

Molecular Weight: 22 kDa

Gene ID: 28511

UniProt: Q9NYR9