NEK3 antibody

Catalog No. ABIN7116884

The Rabbit Polyclonal anti-NEK3 antibody has been validated for WB and ELISA. It is suitable to detect NEK3 in samples from Human, Mouse and Rat.

Quick Overview for NEK3 antibody (ABIN7116884)

Target: NEK3 (NIMA related kinase 3 (NEK3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEK3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NEK3 Antibody

Purpose: NEK3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: NIMA(never in mitosis gene a)-related kinase 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NEK3

Target: NEK3 (NIMA related kinase 3 (NEK3))

Alternative Name: NEK3

Background:

Synonyms: Serine/threonine-protein kinase Nek3|HSPK 36|Never in mitosis A-related kinase 3 (NimA-related protein kinase 3)|NEK3

Background: Protein kinase which influences neuronal morphogenesis and polarity through effects on microtubules. Regulates microtubule acetylation in neurons. Contributes to prolactin-mediated phosphorylation of PXN and VAV2. Implicated in prolactin-mediated cytoskeletal reorganization and motility of breast cancer cells through mechanisms involving RAC1 activation and phosphorylation of PXN and VAV2.

Molecular Weight: 52-60 kDa

Gene ID: 4752

UniProt: P51956