Nitrilase 1 antibody

Catalog No. ABIN7116897

This anti-Nitrilase 1 antibody is a Rabbit Polyclonal antibody detecting Nitrilase 1 in WB, ELISA and IHC. Suitable for Human, Rat and Mouse.

Quick Overview for Nitrilase 1 antibody (ABIN7116897)

Target: Nitrilase 1 (NIT1)

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Nitrilase 1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Nitrilase 1 Antibody

Purpose: NIT1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nitrilase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Nitrilase 1

Target: Nitrilase 1 (NIT1)

Alternative Name: NIT1

Background:

Synonyms: Deaminated glutathione amidase (dGSH amidase)|Nitrilase homolog 1|NIT1

Background: Plays a role in cell growth and apoptosis: loss of expression promotes cell growth and resistance to DNA damage stress. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells, this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells. Has apparently no omega-amidase activity such as NIT2(By similarity).

Molecular Weight: 36 kDa

Gene ID: 4817

UniProt: Q86X76