NXF1 antibody (AA 426-619)

Catalog No. ABIN7117015

This Rabbit Polyclonal antibody specifically detects NXF1 in WB, ELISA, IHC and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for NXF1 antibody (AA 426-619) (ABIN7117015)

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NXF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NXF1 Antibody

Binding Specificity: AA 426-619

Purpose: NXF1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 426-619aa

Immunogen: nuclear RNA export factor 1

Isotype: IgG

Application Details

Application Notes: WB : 1:500-1:1000, IHC : 1:20-1:200, IF : 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Alternative Name: NXF1

Background:

Synonyms: Nuclear RNA export factor 1|Tip-associated protein|Tip-associating protein|mRNA export factor TAP|NXF1|TAP

Background: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements(CTE) and in the export of mRNA from the nucleus to the cytoplasm(TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export.

Molecular Weight: 66-70 kDa

Gene ID: 10482

UniProt: Q9UBU9