NUMB antibody

Catalog No. ABIN7117090

This Mouse Monoclonal antibody specifically detects NUMB in WB, IHC, ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for NUMB antibody (ABIN7117090)

Target: NUMB (Numb Homolog (NUMB))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This NUMB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Clone: 0E11

Product Details anti-NUMB Antibody

Purification: Protein A+G purification

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: numb homolog(Drosophila)

Isotype: IgG2a

Application Details

Application Notes: WB: 1:200-1:1000, IHC: 1:50-1:500, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for NUMB

Target: NUMB (Numb Homolog (NUMB))

Alternative Name: NUMB

Background: Synonyms: Background:Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells(RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone(SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage.

Molecular Weight: 68 kDa

Gene ID: 8650

UniProt: P49757

Pathways: Cell-Cell Junction Organization