ORC6 antibody

Catalog No. ABIN7117136

The Rabbit Polyclonal anti-ORC6 antibody is suitable to detect ORC6 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for ORC6 antibody (ABIN7117136)

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ORC6 Antibody

Purpose: ORC6 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: origin recognition complex, subunit 6 like(yeast)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ORC6

Target: ORC6 (Origin Recognition Complex, Subunit 6 (ORC6))

Alternative Name: ORC6

Background:

Synonyms: Origin recognition complex subunit 6|ORC6|ORC6L

Background: Component of the origin recognition complex(ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Does not bind histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3.

Molecular Weight: 28 kDa

Gene ID: 23594

UniProt: Q9Y5N6

Pathways: Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA