OSBPL10 antibody

Catalog No. ABIN7117172

Product Details anti-OSBPL10 Antibody

Target: OSBPL10 (Oxysterol Binding Protein-Like 10 (OSBPL10))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OSBPL10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: oxysterol binding protein-like 10

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for OSBPL10

Target: OSBPL10 (Oxysterol Binding Protein-Like 10 (OSBPL10))

Alternative Name: OSBPL10 (OSBPL10 Products)

Synonyms: ORP10 antibody, OSBP9 antibody, 4933433D06Rik antibody, C820004B04Rik antibody, OPR-10 antibody, RGD1561652 antibody, oxysterol binding protein like 10 antibody, oxysterol binding protein-like 10b antibody, oxysterol-binding protein-related protein 10 antibody, oxysterol binding protein-like 10 antibody, OSBPL10 antibody, osbpl10b antibody, LOC100457777 antibody, osbpl10 antibody, LOC100526184 antibody, Osbpl10 antibody

Background: Synonyms:ORP10, OSBP9 Background:Probable lipid transporter involved in lipid countertransport between the endoplasmic reticulum and the plasma membrane. Its ability to bind phosphatidylserine, suggests that it specifically exchanges phosphatidylserine with phosphatidylinositol 4-phosphate(PI4P), delivering phosphatidylserine to the plasma membrane in exchange for PI4P(PubMed:23934110)(Probable). Plays a role in negative regulation of lipid biosynthesis(PubMed:19554302). Negatively regulates APOB secretion from hepatocytes(PubMed:19554302, PubMed:22906437). Binds cholesterol and acidic phospholipids(PubMed:22906437). Also binds 25-hydroxycholesterol(PubMed:17428193). Binds phosphatidylserine(PubMed:23934110).

Molecular Weight: 75-80kd,64kd

Gene ID: 114884

UniProt: Q9BXB5