Parvin alpha antibody

Catalog No. ABIN7117241

The Rabbit Polyclonal anti-Parvin alpha antibody is suitable to detect Parvin alpha in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for Parvin alpha antibody (ABIN7117241)

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Parvin alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Parvin alpha Antibody

Purpose: PARVA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: parvin, alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for Parvin alpha

Target: Parvin alpha (PARVA) (Parvin, alpha (PARVA))

Alternative Name: PARVA

Background:

Synonyms: Alpha-parvin|Actopaxin|CH-ILKBP|Calponin-like integrin-linked kinase-binding protein|Matrix-remodeling-associated protein 2|PARVA|MXRA2

Background: Plays a role in sarcomere organization and in smooth muscle cell contraction. Required for normal development of the embryonic cardiovascular system, and for normal septation of the heart outflow tract. Plays a role in sprouting angiogenesis and is required for normal adhesion of vascular smooth muscle cells to endothelial cells during blood vessel development(By similarity). Plays a role in the reorganization of the actin cytoskeleton, formation of lamellipodia and ciliogenesis. Plays a role in the establishement of cell polarity, cell adhesion, cell spreading, and directed cell migration.

Molecular Weight: 45-50 kDa

Gene ID: 55742

UniProt: Q9NVD7

Pathways: Smooth Muscle Cell Migration