PSIP1 antibody (AA 306-530)

Catalog No. ABIN7117258

This Rabbit Polyclonal antibody specifically detects PSIP1 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for PSIP1 antibody (AA 306-530) (ABIN7117258)

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSIP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PSIP1 Antibody

Binding Specificity: AA 306-530

Purpose: PSIP1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 306-530aa

Immunogen: PC4 and SFRS1 interacting protein 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PSIP1

Target: PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))

Alternative Name: PSIP1

Background:

Synonyms: PC4 and SFRS1-interacting protein|CLL-associated antigen KW-7|Dense fine speckles 70 kDa protein (DFS 70)|Lens epithelium-derived growth factor|Transcriptional coactivator p75/p52|PSIP1|DFS70|LEDGF|PSIP2

Background: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.

Molecular Weight: 60 kDa

Gene ID: 11168

UniProt: O75475

Pathways: Chromatin Binding, Ribonucleoprotein Complex Subunit Organization