PER2 antibody (AA 1000-1255)

Catalog No. ABIN7117321

This Rabbit Polyclonal antibody specifically detects PER2 in WB, ELISA and IP. It exhibits reactivity toward Human and Mouse.

Quick Overview for PER2 antibody (AA 1000-1255) (ABIN7117321)

Target: PER2 (Period Circadian Protein 2 (PER2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-PER2 Antibody

Binding Specificity: AA 1000-1255

Purpose: PER2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 1000-1255aa

Immunogen: period homolog 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Alternative Name: PER2

Background:

Synonyms: Period circadian protein homolog 2 (hPER2)|Circadian clock protein PERIOD 2|PER2|KIAA0347

Background: PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. PER2 is a negative element in the circadian transcriptional loop. PER2 influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. It negatively regulates CLOCK|NPAS2-BMAL1|BMAL2-induced transactivation. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset.

Molecular Weight: 136 kDa

Gene ID: 5697

UniProt: O15055