PER2 antibody (pSer662)

Catalog No. ABIN7138676

Product Details anti-PER2 Antibody

Target: PER2 (Period Circadian Protein 2 (PER2))

Binding Specificity: pSer662

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PER2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse

Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of serine 662 (A-E-S(p)-V-A) derived from Human Period Circadian Protein 2.

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:1000, IHC:1:50-1:100,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PER2

Target: PER2 (Period Circadian Protein 2 (PER2))

Alternative Name: PER2 (PER2 Products)

Synonyms: FASPS antibody, FASPS1 antibody, mKIAA0347 antibody, mPer2 antibody, rPER2 antibody, gPer2 antibody, fj43b09 antibody, wu:fj43b09 antibody, period circadian regulator 2 antibody, period circadian clock 2 antibody, PER2 antibody, Per2 antibody, per2 antibody

Background:

Background: Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers').

Aliases: Circadian clock protein PERIOD 2 antibody, FASPS antibody, FASPS1 antibody, hPER 2 antibody, hPER2 antibody, KIAA0347 antibody, OTTHUMP00000164476 antibody, PER 2 antibody, PER2 antibody, PER2_HUMAN antibody, Period 2 antibody, Period 2 isoform 1 antibody, Period circadian clock 2 antibody, Period circadian protein 2 antibody, Period circadian protein homolog 2 antibody, Period homolog 2 (Drosophila) antibody, Period homolog 2 antibody, Period, Drosophila, homolog of, 2 antibody, Period2 antibody

UniProt: O15055