PEX3 antibody
Quick Overview for PEX3 antibody (ABIN7117349)
Target
See all PEX3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- peroxisomal biogenesis factor 3
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Isotype
- IgG
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Application Notes
- WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Expiry Date
- 12 months
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- PEX3 (Peroxisomal Biogenesis Factor 3 (PEX3))
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Alternative Name
- PEX3
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Background
- Synonyms: Background:The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS).
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Molecular Weight
- 37 kDa
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Gene ID
- 8504
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UniProt
- P56589
Target
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