PHPT1 antibody

Catalog No. ABIN7117456

This Rabbit Polyclonal antibody specifically detects PHPT1 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for PHPT1 antibody (ABIN7117456)

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHPT1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PHPT1 Antibody

Purpose: PHPT1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: phosphohistidine phosphatase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PHPT1

Target: PHPT1 (phosphohistidine Phosphatase 1 (PHPT1))

Alternative Name: PHPT1

Background:

Synonyms: 14 kDa phosphohistidine phosphatase|Phosphohistidine phosphatase 1 (PHPT1)|Protein histidine phosphatase (PHP)|Protein janus-A homolog|PHPT1|PHP14

Background: This gene encodes an enzyme that catalyzes the reversible dephosphorylation of histidine residues in proteins. It may be involved in the dephosphorylation of G-beta and ATP citrate lyase and in negatively regulating CD4 T lymphocytes by dephosphorylation and inhibition of KCa3.1 channels. Alternative splicing results in multiple transcript variants.

Molecular Weight: 14 kDa

Gene ID: 29085

UniProt: Q9NRX4

Pathways: Positive Regulation of Peptide Hormone Secretion