PHKG2 antibody

Catalog No. ABIN7117512

This anti-PHKG2 antibody is a Rabbit Polyclonal antibody detecting PHKG2 in WB, IHC and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for PHKG2 antibody (ABIN7117512)

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-PHKG2 Antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: phosphorylase kinase, gamma 2 (testis)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for PHKG2

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Alternative Name: PHKG2

Background: Synonyms: Background:Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Molecular Weight: 46 kDa

Gene ID: 5261

UniProt: P15735

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process